Typically present in women in their late reproductive or postmenopausal years with an average age at presentation papilloma intraductal central 48 years Clinical presentation Patients typically report a bloody or clear serosanguinous nipple discharge of fewer than six months duration. Pathology Intraductal papillomas are broadly cancer endometrial williams slideshare into central and peripheral types, with the central ones usually being solitary and subareolar in location within a major duct, while peripheral types tending to be multiple within the terminal duct lobular unit.
Papillomas often present in the subareolar region. Mammography Mammograms are frequently normal particularly with small intraductal papillomas.
When imaging findings are present, they include solitary or multiple dilated ducts, a circumscribed benign-appearing mass often subareolar in locationor a cluster of calcifications. Breast ultrasound Papilloma may be seen as a well-defined solid nodule or intraductal mass which may either papilloma intraductal central a duct or be partially outlined by fluid - either within a duct or by forming a cyst.
Colour Doppler will demonstrate a vascular stalk.