Prostate cancer benign prostatic hyperplasia, Endocrinology

Source: Romanian Journal of Infectious Diseases.

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Author s : Nicolae, Ilinca; Ene, Corina-Daniela; Georgescu, Simona Roxana Abstract: Molecular pathology of benign prostatic papilloma tumore gola is multifactorial and involves endocrine, biochemical, immunological interactions. The mechanisms involved in the onset and progression of benign prostatic hyperplasia are: infections, 50 years of age, hormones and neurotransmitters imbalances, inflammation, oxidative stress.

The potential role of glycosylation in the pathogenesis of prostate disease has been neglected.

In this study we documented the profile of gangliosides in normal and pathological prostatic tissues together with the pathologic changes seen in the level of extracellular gangliosides in patients with prostate pathology. Analysis of the data in the literature suggests that gangliosides may represent immunologic markers useful in the differential diagnosis between prostate cancer and benign prostatic hyperplasia.

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